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Treatment with either NR or the PARP inhibitor Olaparib resulted in improvements at the mitochondrial and proteostasis level

2.9 Cell culture and treatment Mouse colon epithelial cells (MCECs) were cultured in high-glucose Dulbeccos Modified Eagle Medium, supplemented with 10% fetal bovine serum and 1% penicillin-streptomycin (P/S), in a humidified incubator with 5% CO 2 at 37C

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(4) mass-transfer limitations between enzymes and substrates (Luckarift et al., 2004