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These may include: Nausea and stomach upset Particularly when taken on an empty stomach Diarrhoea May be more common with higher doses Loss of appetite Occasionally reported in sensitive individuals Abdominal discomfort Mild cramping or bloating Beyond digestive symptoms, some individuals report non-gastrointestinal effects such as headaches, dizziness, fatigue, or skin rashes

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We are also interested in the correlated changes across all three modalities, as the comparison between brain metabolism and function has important implications for medical imaging biomarkers, both when metabolism and function are correlated [27] and also when they diverge [28]