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You will see progress as the skin renews itself over time

The primary end point (a composite of death from cardiovascular causes, non-fatal myocardial infarction, or non-fatal stroke) occurred in 305 patients with alogliptin (11.3%) and in 316 patients with placebo (11.8%), which was not significantly different

The cardiovascular safety of TRESIBA was evaluated in one double-blinded, event-driven trial of 2-year median duration in patients with type 2 diabetes at high risk of cardiovascular events [see Clinical Studies (14)]