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The nasal administration route enables efficient drug delivery by avoiding degradation in gastric juices and improving systemic absorption
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GPX4-dependent chondrocyte ferroptosis has recently attracted more attention in studies related to OA (203, 204).GPX4 can regulate the development of chondrocyte ferroptosis (203, 205)
A broadly consistent pattern was observed across agents, characterized by an early peak after treatment initiation, followed by a decline and a modest increase with longer exposure
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