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This triggers an insulin spike, which is necessary to activate the sodium-dependent carnitine transporter (OCTN2) that moves carnitine from the bloodstream into the muscle cells
On the outer mitochondrial membrane, CPTI (carnitine-palmitoyl transferase I) catalyzes the transfer of medium/long-chain fatty acids esterified to coenzyme A (CoA) to L-carnitine
R., Greene, M., Ainsworth, A
HbA1c and Hypoglycemia Reductions at 24 and 52 Weeks With Sotagliflozin in Combination With Insulin in Adults With Type 1 Diabetes: The European inTandem2 Study
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