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Tirzepatide came in at 1.73, still elevated but noticeably lower than semaglutide

Treated female mice that were given DSIP from three months of age until they died, for 5 consecutive days each month, showed a 2.6-fold decrease in tumor development and a 22.6% lower frequency of chromosomal defects in the bone marrow cells

We note that the only difference in the calculation for the full conversion factor and the calculation for the reduced conversion factor is that the full ( conversion factor uses the full OPD update, and the reduced conversion factor uses the reduced OPD update