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3.6 Melanogenesis reduction Ultraviolet radiation stimulates melanogenesis through activation of the microphthalmia-associated transcription factor (MITF)-regulated pathway, promoting tyrosinase (TYR)-dependent melanin synthesis in melanosomes to protect against DNA damage, while excessive production leads to hyperpigmentation disorders (Kim et al., 2021)

Rodriguez-Iturbe B, Sepassi L, Quiroz Y, Ni Z, Wallace DC, Vaziri ND

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Participants consumed either fish oil (providing 860 milligrams of DHA and 120 milligrams of EPA per day) or a placebo (1 gram of corn oil per day) for 12 weeks