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1), with an abrupt activation of a specific gene module upon entering phase 4

Identification of Novel Protein Targets of Dimethyl Fumarate Modification in Neurons and Astrocytes Reveals Actions Independent of Nrf2 Stabilization

The field of ALS has advanced significantly over the last decade, with rapid progress in understanding the genetic architecture and the pathophysiological mechanisms of the disease, and in the development of robust, exploitable preclinical model systems

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