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FDA-Labeled Indications for Chronic Weight Management As of early 2026, two medications carry FDA indications specifically for chronic weight management in adults: Wegovy (semaglutide 2.4 mg) approved 2021 Zepbound (tirzepatide) approved 2023 Liraglutide (Saxenda) is also approved for weight management but has been largely supplanted by the once-weekly options

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A 500 mcg dose of a 90% pure product is not the same as a 500 mcg dose of a 99%+ pure product