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The authors also point out that in some rare genetic disorders of B12 metabolism, the active forms may be required, and that smokers, who tend to have an excess of thiocyanate in their blood, may benefit from a taking a form other than cyano-B12

PLoS One Rosas HD, Chen YI, Doros G, Salat DH, Chen N, Kwong KK et al (2012) Alterations in brain transition metals in Huntington disease: an evolving and intricate story

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