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Throughout the study, weight loss was gradual, with no plateau observed at 13 weeks, and the drug was found to be safe and well-tolerated (see Figure 1)

Eating smaller portions, slowing down at meals, and avoiding heavy, fatty, or spicy foods can significantly reduce nausea

Recent studies generally suggest that between approximately 25% and 75% of bariatric surgery patients wearing continuous glucose monitors, or CGMs, exhibited PBH

In agreement with previous analyses ( Table 2 , Supplementary Figure 5 , and Supplementary Table 8 )

Quick Answer: Tirzepatide likely has minimal direct blood-brain barrier penetration due to its large molecular size (approximately 4,800 daltons), but produces central nervous system effects through indirect pathways