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Consider combining comprehensive training strategies, periodized phases with recovery planning, and balanced approaches combining power development with endurance integration

Images were acquired using a PANNORAMIC Midi Slide Scanner (3DHISTECH), and quantitative analyses performed using ImageJ (NIH)

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Key molecular changes included the activation of tumor-suppressing pathways and the relocalization of the mTORC1 inhibitor DDIT4/REDD1, indicating a shift toward non-oxidative energy metabolism and reduce of tumor cell growth