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This process is driven by the inactivation of glutathione peroxidase 4 (GPX4) and the pathological accumulation of lipid hydroperoxides (LPOs) within cellular membranes (Stockwell et al., 2017

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Interestingly, we found that efficient phase transfer from water to dichloromethane only occurs in the pH range of 6.09.6, at which the amine groups in DDA are protonated (positively charged) and the carboxylic acid groups in GSH are deprotonated (negatively charged) supporting the electrostatic nature of the HIP in DDA-GSH-AuNCs (Fig

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Imagine liposomal glutathione as a well-packed suitcaseeverything stays intact during the trip to your cells