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Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein-Coupled Receptor FFAR2

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It is shown to be increasing dopamine-B-hydroxylase levels, decreasing extracellular dopamine release, increasing DAT surface expression, increasing dopamine turnover, and suppressing projections to NAc, GLP-1R agonists might be decreasing palatable food or drug-induced phasic dopaminergic signaling in reward-related areas and therefore decreasing conditioned consummatory behavior