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An excess of I can increase the antigenicity of Tg, stimulate the production of cytokines and chemokines, which can increase the accumulation of immunocompetent cells in the thyroid gland, increase the level of OS in thyrocytes, stimulate lipid peroxidation and damage to thyroid tissue (43)

The second antibody was added in 1.5 molar excess of the intermediate construct and coupled for at least 3 h, typically overnight

Adiponectin attenuates NADPH oxidase-mediated oxidative stress and neuronal damage induced by cerebral ischemia-reperfusion injury

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