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Slower titration is worth considering if: Nausea persists beyond 2 weeks at your current dose You experience significant GI symptoms that interfere with daily function Your body aches or muscle pain are severe You are losing weight faster than 1 to 2 percent of body weight per week (too-rapid weight loss increases muscle loss risk) Some researchers use a 6 or 8-week interval between dose increases instead of the standard 4 weeks

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doi: 10.1089/ars.2011.4198

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That being said, while assessing the conduction velocity of the action potential through the fragment of the regenerating sciatic nerve, conduction velocity was simultaneously observed at the area of the initial suture [1]

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