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treated their spheroids with 17-estradiol, which is the most potent and naturally occurring human estrogen ( 4 Future directions - utilizing 3D adipose tissue technologies for lipedema research As the lipedema field moves toward more comprehensive models, several 3D technologies from general adipose research offer high potential for lipedema applications

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MO has been used to ameliorate nephrotoxicity induced by titanium dioxide nanoparticles (TiO 2 NPs) ( 2 NP-treated rats were fed with an MO leaf extract, and the expression of kidney 222 injury molecule 1 (KIM-1), NF-B, TNF-, and heat shock protein 70 (HSP-70) were markedly 223 decreased, while the expression of NRF-2 and heme oxygenase 1 (HO-1) were significantly 224 upregulated compared with those in control groups