Considering the increasing incidence of DM and obesity in cats and dogs, the aim of this review is to summarize the available information about the physiological and pharmacological actions of GLP-1 in domestic animals and discuss about its potential applications in veterinary medicine
References Chen JH, Tsai MS, Chen CY, et al
A case in point is the so-called glucose-fatty acid cycle, a prime example of tightly coordinated cellular energy metabolism that provides a mechanistic reciprocal regulation of lipid and glucose oxidation to maintain cell homoeostasis and to avoid mitochondrial overloading
Data availability All original data including uncropped Western Blot images can be found in the Supplementary Dataset File
Laboratory studies use these receptor systems to investigate peptide mediated signaling pathways involved in neuroendocrine communication, nutrient sensing, and metabolic regulation within experimental models