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GLP-1 receptor agonists mimic this natural hormone , binding to GLP-1 receptors found throughout the body, including the pancreas, brain, gastrointestinal tract, and cardiovascular system

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As seen in the compound 2GLP-1RG s complex, two cholesterol molecules were also found in the identical position of the compound 2GLP-1GLP-1RG s and compound 2LY3502970GLP-1RG s complexes, implying a common role for the two cholesterol molecules