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High blood sugar In animal studies, the antioxidants in chanca piedra have been able to improve fasting blood sugar levels, which can help with blood sugar management ( Still, this doesnt necessarily mean that chanca piedra would have the same effect in humans

Kidney and Liver Concerns : Individuals with kidney or liver disease should avoid high doses, as these organs process amino acids

Further support was provided from electrophysiological recordings of NAc slices, in which both Ex4 and liraglutide, but not dulaglutide, reduced excitatory neurotransmission in the NAc, without affecting inhibitory neurotransmission (64)

doi: 10.1007/s00125-024-06273-7 23 WallaceASChangARShinJIReiderJEchouffo-TcheuguiJBGramsMEet al

Heating the GO at various degrees in distilled water for various lengths of time