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As of March 2026, more than 3,363 lawsuits have been filed across both MDLs

Treatment should be stopped if at least 5% weight loss has not been achieved after 12 weeks on the maintenance dose, and treatment should not continue beyond 2 years

Zhou, D., Zhang, J., Xiao, C., Mo, C., & Ding, B

T-VEC is a genetically modified herpes simplex virus type 1 (HSV-1) with reduced virulence and selective proliferation in tumors, encoding GM-CSF, which promotes the priming of T cell responses

Temperature excursions during shipping represent a particular concern because the duration and degree of temperature elevation are unknown