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Theyre also important for brain health and hormone production

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The Numbers That Matter: In the landmark SURMOUNT-5 trial published in the New England Journal of Medicine in May 2025, participants taking tirzepatide lost an average of 20.2% of their body weight over 72 weeks, compared to 13.7% with semaglutide

Continuous variables were summarized descriptively (n, mean, standard deviation, median, minimum, maximum), and categorical variables by frequency and percentage

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