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The first step in the de novo cellular synthesis of CoQ 10 consists of the synthesis of the benzoquinone ring, initiated with 4-hydroxybenzoate together with the side chain precursor, acetyl-CoA [10,11]

Antioxidants 12(4):965

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To improve transparency, an adapted PRISMA-style flow diagram documenting identification, screening, eligibility assessment, de-duplication, and selection of the RCT evidence base and the proof-of-concept Bayesian subset is provided in the Supplementary Appendix Figure 1, together with details of the search strategy, screening process, and data extraction