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Additionally, while a benefit of GLP-1s has generally shown positive cardiovascular outcomes data (less heart attacks, less strokes, less cardiovascular death), I predict that this benefit wont be there if patients have sarcopenic obesity, said Kumar

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Female patients accounted for the highest proportion of ICSRs (45.8%), and 6,634 (98.3%) cases were classified as serious

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The increased lipid content in muscle could be attributed to the down-regulation of the mRNA levels of lipolytic genes ( CPT1A and ATGL ) and to the increased activity of LPL