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hog1 (JC45)
Glutathione is usually well-tolerated, but as with any medical intervention, there can be side effects
Heat acts as a powerful catalyst, dramatically speeding up these oxidative reactions
The chemical reactions governing the detoxification of H 2 O 2 by catalase, Prxs and GPxs are as follow, Catalase: GPx: Prx (typical 2-Cys and atypical 2-Cys): Prx (1-Cys): where GPX1 and GPX0 are respectively the reduced and oxidized form of GPx-1, GSSG is glutathione disulphide, GS-GPx is the glutathione-enzyme complex, Prx(SH)(SH), Prx(SOH)(SH) are respectively the reduced and oxidized form typical 2-Cys and atypical 2-Cys of Prx, Prx(SH), Prx(SOH) are respectively the reduced and oxidized form typical 1-Cys of Prx, Trx(SH)(SH), Trx(S)(S) are respectively the reduced and oxidized form of thioredoxin and Prx(SO 2 H)(SH) is the hyperoxidized form of Prx