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Rates of gout were also slightly higher 7.4% for GLP-1 users versus 6.6% for nonusers an increased risk about 12%

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(5) Increased cardiomyocyte contractilityRestoring cardiac contractility and pumping efficiency is a key target of gene therapy, particularly through SERCA2a and its regulatory proteins, which modulate intracellular Ca dynamics to alleviate symptoms in patients with HFrEF and improve long-term outcomes (Fig

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