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At the 12 mg dose, 86% of participants achieved normal liver fat levels

Tirzepatide and metformin together represent a powerful, evidence-based combination for managing type 2 diabetes when single-agent therapy fails to achieve glycemic targets

In one study, the CD44 rs1467558 polymorphism was reported to be significantly associated with an ALT rise in independent cohorts of patients given a therapeutic dose of 4 g/day of paracetamol over 7 days [42]

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