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While MIC b12 dosages are safe for short-term use, there have been some reports of side effects when used over a long period

In small studies, most patients with chronic knee pain or chronic bladder pain reported major improvement after BPC157 treatment

Some researchers also track NAD+ metabolite levels via urinary nicotinamide excretion to confirm functional NNMT inhibition, though this is not standard practice

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[20] [21] It also causes self-limiting hypertension, however due to the hypotension affects of cyanide and carbon monoxide poisoning, it is not bad