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And as for that first month, it is less about what you lose and more about what you learn, because what you are really discovering is what it feels like to not be controlled by food for the first time in a very long time.

A post hoc analysis of the phase IIb trial showed that tirzepatide was associated with a reduction in the level of high-sensitivity ICAM-1, CRP, and YKL-40 after 26 weeks of treatment in a dose-dependent manner [83, 103]

Things such as reducing meal size, eating only when hungry, and practicing mindfulness while eating, which includes stopping when you feel full, can all help ease gastrointestinal issues, says Criner

If you think you might benefit from medications listed as controlled substances, we recommend looking into Talkiatry, which also offers longer appointment times with board-certified psychiatrists

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