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Morrison AE, Fleming S, Levy MJ

A multivitamin may be considered for patients with significantly reduced food intake or documented nutritional gaps, though the US Preventive Services Task Force notes insufficient evidence for routine multivitamin use in generally healthy adults

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[9] A standard ladder calibrated for the average trial participant will therefore overshoot for a meaningful share of women, delivering more weight loss than they wanted along with more nausea than anyone wants

The sections that follow apply this framework to specific physiological domains, beginning with metabolic and energy-balance peptides beyond the incretin family