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Vitamin B12 is important for a number of vital functions in the body, such as growth and brain function

Some are actively working toward weight management goals and want metabolic support alongside a healthy diet and exercise routine

Since NNMT is expressed in adipose, hepatic, and gut tissues 50,51,52 , and these tissues heavily cross-talk with the gut microbiome 53,54,55 , NNMTi treatment or its resulting weight loss effects 8,9 may modulate the microbiome

(3) Dong Rak Kwon and Gi Young Park (2015) Effect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis Model Annals of Clinical and Laboratory Science, 2015 Summer, Volume 45 (Issues 4), Pages 426-32

Injections bypass that step, so more B12 becomes available to tissues