Both are unlicensed in the UK, and their combined use should only ever be considered under close specialist supervision, ideally within a formal clinical trial setting
Given that the IC 100 concentration of niclosamide required to completely prevent viral replication in SARS-CoV-2 infected Calu-3 lung cells as measured by Ko et al (34) as 2M, a 20uM niclosamide solution nasal spray is 10x this IC 100
n = 28) and comparable women without the history of tamoxifen treatment ( n = 11)
Low glutathione S-transferase P1 levels are associated with higher mortality in COVID-19 patients, and high levels of glutathione S-transferase P1 possibly offer protection for cellular redox reactions in severe COVID-19 infection, preventing deterioration especially in patients with co-morbidities like diabetes (Kumar D.S
These supplements can be used together strategically, with enzymes taken alongside meals to support digestion in the moment, and a synbiotic taken daily to support baseline gut health over time