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aim is to provide at least 120 - 140 meg / litre of plasma over at least 12 hrs, preferably over at least 24 hrs period, more preferably over at least 48 hrs and most preferably over at least 72 hrs

Notably, the American Diabetes Association advocates for the utilization of GLP-1 RAs with established cardiovascular benefits in patients diagnosed with type 2 diabetes and concurrent cardiovascular disease

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We know that corporate capture has somewhat happened with the FDA, somewhat happened with Congress and the Senate

[1] [12] Additionally, GLP-1 receptor agonists slow gastric emptying and act on appetite centres in the brain, promoting satiety and reducing food intake