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The DPP4 inhibitor failed to improve glucose tolerance or -cell function while GLP-1r signaling was blocked in RYGB patients

Lillys pricing strategy with first-in-class drugs has been premium pricing relative to competitor classes (tirzepatide priced as premium to semaglutide on weight loss data, but discounted from Wegovy on list)

REDEFINE-1) reported 22.7% weight loss at 68 weeks when paired with semaglutide

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