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Raam, L

Precision diagnosis and future directions There are compelling reasons for seeking biologically meaningful classification systems based on diabetes heterogeneity across age groups, but greater evidence on the relative contribution of -cell dysfunction vs Direct evidence for insulin resistance in aging-associated diabetes is needed to further define SAGE-DM as an aging-related phenotype Future research priorities include: 1

A 2020 study measuring cord blood biomarkers found dose-response relationships: children with highest cord blood levels of NAPQI-related metabolites faced 2-3x higher odds of attention/focus disorder

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