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Superimposition of the hTrx1 structures obtained in the hTrxR1hTrx1 complexes with published structures in the uncomplexed form (PDB codes 2hsh 18 , and 1aiu 17 ) also shows r.m.s

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Novartis Pluvicto established radioligand therapy as a commercial reality (2022+): Lutetium-177 PSMA-617 (Pluvicto) for metastatic castration-resistant prostate cancer achieved rapid adoption post-2022 launch, validating the peptide receptor radionuclide therapy platform and creating a template for multiple follow-on radioligand therapy programmes