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Disruptions in this process leads to hyperbilirubinemia, categorised as unconjugated or conjugated, depending on the specific metabolic defect [38, 39]

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Freshly made solutions of equal volume 5,5-dithio-bis(2-nitrobenzoic acid) and glutathione reductase with concentrations of 0.33 g l 1 and 1.67 units per ml, respectively, were mixed with lysate to a final volume of 140 l

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They can help with mild pigmentation and radiance, but have limited penetration into deeper layers