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J Clin Biochem 1984;17:99-107

Synthetic scaffolds made of calcium-phosphate graft materials provide an osteoconductive scaffold for new bone to grow into, while also avoiding the need to harvest bone from the patient, which often previously led to increased pain and recovery time

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The vitamin is also essential for DNA synthesis and red blood cell formation, meaning deficiency can have wide-ranging effects beyond the nervous system, including fatigue and cognitive difficulties