Cotadutide (MEDI0382) is the most extensively developed dual GLP-1/glucagon receptor agonist, showing significant improvements in glucose control, BW (likely mediated by reduced energy intake rather than increased energy expenditure), hepatic fat, and albuminuria in a small RCT on patients with T2D and overweight or obesity 45,46
Most of whats known comes from animal studies, anecdotal reports, and underground use, leaving big questions around safety, purity, and long-term effects
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This product is not a dietary supplement, medication, or food additive
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