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By binding to GLP-1 receptors throughout the body, they produce a powerful, sustained version of what your natural hormone does but for hours or days at a time rather than minutes

10.1007/s13679-024-00572-1 25 GuptaP

Similarly, in the human chondrocyte SW1353 cell line, dulaglutide inhibited AGEs-induced activation of NFkB and the expression of pro-inflammatory cytokines [99], whilst in human knee OA primary articular chondrocytes, lixisenatide reduced mRNA ad protein expression of TNF-, IL-6 and IL-7 [100]

That bacterial fermentation produces hydrogen, methane, and carbon dioxide, which accumulate as gas in your intestinal tract

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