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Data extraction and synthesis were performed iteratively, with emphasis on clinical relevance and perioperative applicability

The way patients perceive changes in their treatment can have a significant impact on outcomes, as some may delay seeking medical advice or adjusting their treatment regimen without consulting a healthcare professional

S., Liu, R., Zhao, Y., & ACHIEVE-3 Investigators (2026)

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Company-reported Phase 3 topline results have circulated in 20252026, and a regulatory filing has been anticipated, but retatrutide is not FDA- or EMA-approved and is not available as a prescription product