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Headache represents another occasionally reported effect, potentially related to the peptide's vasodilatory properties

Both clonidine and propranolol begin to lower blood pressure within an hour, but full effects may take several days to stabilize, depending on dosage and individual response

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Type I cells seem to have glia like function as they express several ion channels (inward rectifying K+ channel [ROMK], glutamate-aspartate transporter [GLAST], ENaC) which are supposed to clear ion currents [222335]

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