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2019 Dec;39(4):529-544

Its role is incompletely defined but it enables talin binding either directly or indirectly

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Women then can have some or all of the following symptoms: Menstrual periods that are infrequent, irregular or absent Difficulty getting pregnant Obesity (in 40% to 50% of women with this condition) Acne Hair growth in the beard area, upper lip, sideburns, chest, the area around nipples or the lower abdomen along the midline Darkened, thickened skin, sometimes appearing similar to velvet, in the armpits High blood pressure, high blood sugar or a cholesterol problem Diagnosis If your periods are irregular, a pregnancy test should be done

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