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This adaptation persists after stopping GLP-1 medications and contributes to weight regain

eat right, exercise, and see our health care professional when necessary

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NICE guidance (NG28) recommends: Consider reducing sulfonylurea or insulin doses when starting Ozempic to mitigate hypoglycaemia risk, with adjustments guided by blood glucose monitoring Maintaining metformin at existing doses unless contraindicated Reviewing all medications that affect glucose metabolism Never stopping insulin abruptly , as this could lead to diabetic ketoacidosis (DKA) Lifestyle optimisation enhances Ozempic's effectiveness