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As a consequence, interpretation of omics data must consider the bidirectional gut-brain connection which facilitates the delivery of metabolites to the CNS and impacts GI function/microbiota after brain injury [107]

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10.1002/jor.20089 85 StrangS

Protein deficiency-induced behavioral abnormalities and neurotransmitter loss in aged mice are ameliorated by essential amino acids

By inhibiting NNMT activity, 5-Amino-1MQ has been investigated for its potential to alter intracellular nicotinamide metabolism, increase nicotinamide adenine dinucleotide (NAD) availability, and improve mitochondrial energy utilization