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However, it remains unclear whether a link between the two actually exists

The added targets generally correlate with larger weight reductions in trials

Arnold M, Pandeya N, Byrnes G, Renehan AG, Stevens GA, Ezzati M, et al

Homocysteine-Lowering by B Vitamins Slows the Rate of Accelerated Brain Atrophy in Mild Cognitive Impairment: A Randomized Controlled Trial. PloS One, vol