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In essence, GLP-1 effects provide safe and effective glucose control for diabetic patients and have achieved up to 20% weight loss in overweight and obese individuals, a milestone previously unseen with other therapeutic options

It was found that SP had no impact on the mRNA transcription of Keap1 , whereas the transcription levels of Nrf2 and Homx1 were significantly elevated (Supplementary Fig

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3C-E, ATG7 and LC3II/I levels were significantly increased in HUVECs exposure to H 2 O 2, which were attenuated by GLP-1 treatment