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Frailty in individuals may include at least three of the following symptoms: unintentional weight loss, exhaustion (poor endurance), weakness (low grip strength), slowness, and physical inactivity (115)
End-stage renal disease L-Carnitine and short/medium-chain acylcarnitine molecules are removed from the circulation during hemodialysis
ESC Heart Fail
Moreover, because carnitine also offers antioxidant and anti-inflammatory effects, it has been shown to reduce markers of vascular injury in patients undergoing hemodialysis and in those with peripheral vascular disease (11, 12)
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