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Patients experiencing significant side effects may benefit from a slower titration schedule or temporary dose reduction, and dose escalation should be deferred while significant gastrointestinal symptoms persist

Unlike older medications that target just one pathway, tirzepatide weight loss treatment works by activating two crucial hormonal systems: GLP-1 and GIP receptors

The 15-amino-acid synthetic analogue used in research is stable in human gastric juice and does not require a carrier for in vitro work

As new drug classes enter the space, especially those targeting metabolic disease and body composition, well need to start thinking beyond the prescription pad

The MHRA and EMA have reviewed this evidence, and the Summary of Product Characteristics (SmPC) for semaglutide (Ozempic, Wegovy) specifically advises that patients with diabetic retinopathy should be closely monitored during treatment, particularly during periods of rapid glycaemic improvement