Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1)
We know this because scientists have studied data from clinical trials examining Mounjaro's weight loss potential
The discipline pays off in consistent results, minimal complications, and a comfortable injection experience that you can maintain for as long as your semaglutide protocol continues
But the really impressive numbers came from the SURPASS-5 trial, where tirzepatide reduced total cholesterol by 12.9%, LDL cholesterol by 15.5%, and triglycerides by a substantial 24.9%, while increasing HDL cholesterol by 0.9%
Tirzepatide is composed of 39 amino acids, is amidated at the C-terminal, conjugates a C20 fatty diacid moiety via a spacer connected to Lys 20 , and has a half-life of 116.7 h